EigoPro 2級 読解 — The Accidental Discovery of Antibiotics

The Accidental Discovery of Antibiotics Some of the greatest discoveries in science have happened not through careful planning, but by accident. One of the most famous examples is the discovery of penicillin, the world's first antibiotic — a medicine that kills harmful bacteria. It was found in 1928 by Alexander Fleming, a Scottish scientist, and it changed medicine forever. The story began when Fleming returned to his London laboratory after a holiday. Before leaving, he had been studying bacteria in small glass dishes, and he had left some of the dishes unwashed on his bench. When he examined them again, he noticed something strange: a spot of blue-green mould was growing in one dish, and all around it, the bacteria had been destroyed. Instead of simply throwing the spoiled dish away, Fleming became curious. He realised that the mould was producing a substance that killed bacteria, and he named it penicillin. It took more than a decade, and the work of many other scientists, to turn Fleming's observation into a usable medicine. But once penicillin could be produced in large amounts, its effect was enormous. Infections that had killed millions of people — from simple cuts that went bad to serious diseases — could suddenly be cured with a short course of treatment. Doctors at the time described it as a miracle. Countless soldiers wounded in the Second World War survived because of it, and average life expectancy rose sharply in the decades that followed. Today, however, doctors face a new problem: bacteria are fighting back. When antibiotics are used too often, or used incorrectly, some bacteria survive and develop resistance, meaning the medicines no longer work against them. Health organisations now urge doctors to prescribe antibiotics only when truly necessary, and urge patients to finish the full course they are given. Fleming himself warned of exactly this danger almost a century ago — proof that listening to scientists matters, even when the news is inconvenient.

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この単元の問題を3問、解説つきで公開しています

2級 · 読解 · 全5

1

What is the main idea of the passage?

  • Penicillin has never actually cured any disease.
  • Antibiotics still work perfectly against all bacteria.
  • Penicillin was discovered by accident and transformed medicine, though resistance is now a problem.
  • Penicillin was developed after years of careful planning.
Phrase

penicillin, found by accident, changed medicine forever

偶然発見されたペニシリンは医学を永遠に変えた

2級読解医学史主旨
ひとことで

記事の主旨は「世界初の抗生物質ペニシリンは1928年フレミングが偶然発見し、医学を一変させたが、今日は耐性菌という新たな課題に直面している」。

選択肢の解説Choice Analysis

Penicillin was discovered by accident and transformed medicine, though resistance is now a problem.

正解

第1段落 "It was found in 1928 by Alexander Fleming ... and it changed medicine forever" が主旨。記事は偶然の発見 → 巨大な影響 → 耐性菌の課題と展開。by accident = 「偶然に」、antibiotic = 「抗生物質」。

  • Penicillin was developed after years of careful planning, and resistance was solved long ago.

    = 長年の綿密な計画で開発 ━ 本文 "not through careful planning, but by accident" と矛盾。

  • Penicillin was used widely for decades but never actually cured any disease.

    = 実際には何の病気も治していない ━ 本文 "Infections ... could suddenly be cured" と矛盾。

  • Antibiotics still work perfectly against all bacteria, so overuse is no longer a worry.

    = 全ての細菌に今も完璧に効く ━ 本文 "the medicines no longer work against them" と矛盾。

Collocation
パターン意味
by accident偶然にbut by accident
harmful bacteria有害な細菌kills harmful bacteria
change ~ forever〜を永遠に変えるchanged medicine forever
the first antibiotic最初の抗生物質the world's first antibiotic
a famous example有名な例One of the most famous examples
例文
  • Penicillin was discovered by accident.

    ペニシリンは偶然発見された。

  • It changed medicine forever.

    それは医学を永遠に変えた。

  • Great discoveries sometimes happen unplanned.

    偉大な発見は時に計画外に起こる。

💡Tip · 覚えるコツ

主旨設問の鉄則 ―― 冒頭 "by accident" + "changed medicine forever" + 末尾の耐性問題を覆う選択肢が正解。誤答は本文と矛盾 (綿密な計画 / 治していない / 完璧に効く) で誘導。

2

How did Fleming discover penicillin?

  • The bacteria in the dish had destroyed the mould.
  • He carefully grew the mould on purpose to kill bacteria.
  • He threw the dish away without looking at it.
  • He noticed that mould in an unwashed dish had destroyed the bacteria around it.
Phrase

a spot of mould was growing, and around it the bacteria had been destroyed

カビの周囲の細菌が死滅していた

2級読解医学史詳細 (発見)
ひとことで

フレミングが休暇から研究室に戻ると、洗わず放置したガラス皿の一つに青緑のカビが生え、その周囲の細菌が死滅していた。汚れた皿を捨てる代わりに好奇心を持ち、カビが細菌を殺す物質を作っていると気づき、ペニシリンと名付けた。

選択肢の解説Choice Analysis

He noticed that mould in an unwashed dish had destroyed the bacteria around it.

正解

第2段落 "he noticed something strange: a spot of blue-green mould was growing in one dish, and all around it, the bacteria had been destroyed. Instead of simply throwing the spoiled dish away, Fleming became curious" より、発見 = 放置した皿のカビの周囲で細菌が死滅mould = 「カビ」、instead of V-ing = 「〜する代わりに」。

  • He grew the mould on purpose in a clean dish in order to test it on bacteria.

    = 細菌を殺すため意図的にカビを培養 ━ 本文は偶然 (unwashed dishes) の発見、意図的ではない。

  • He threw the unwashed dish away without looking at what had grown in it.

    = 見ずに皿を捨てた ━ 本文 "Instead of simply throwing the spoiled dish away" と矛盾。

  • The bacteria in the dish had spread out and destroyed the mould growing there.

    = 皿の細菌がカビを破壊した ━ 本文と主客が逆 (カビが細菌を殺した)。

Collocation
パターン意味
leave ~ unwashed〜を洗わず放置するleft some of the dishes unwashed
notice something strange異変に気づくhe noticed something strange
instead of V-ing〜する代わりにInstead of ... throwing ... away
become curious好奇心を持つFleming became curious
produce a substance物質を作り出すproducing a substance
例文
  • Fleming left his dishes unwashed.

    フレミングは皿を洗わず放置した。

  • Mould had destroyed the bacteria around it.

    カビが周囲の細菌を死滅させていた。

  • His curiosity led to a great discovery.

    彼の好奇心が偉大な発見につながった。

💡Tip · 覚えるコツ

発見設問の鉄則 ―― "noticed something strange" 以下 (mould / bacteria destroyed / became curious) を拾う。誤答は本文を逆転 (意図的 / 捨てた / 主客逆転) で誘導。「捨てる代わりに観察した」が決め手。

3

What effect did penicillin have once it could be mass-produced?

  • Penicillin became a usable medicine immediately in 1928.
  • Penicillin had almost no effect on infections.
  • Deadly infections became curable, and average life expectancy rose sharply.
  • Life expectancy fell after penicillin appeared.
Phrase

infections that had killed millions could suddenly be cured; life expectancy rose sharply

何百万人を殺した感染症が治療可能に、平均寿命が急上昇

2級読解医学史詳細 (影響)
ひとことで

フレミングの観察を実用薬にするには10年以上と多くの科学者の働きを要した。だが大量生産が可能になると効果は絶大で、化膿した切り傷から重病まで、何百万人を殺してきた感染症が短期間の治療で治せるようになった。第二次大戦の無数の負傷兵が生還し、その後の数十年で平均寿命が急上昇した。

選択肢の解説Choice Analysis

Deadly infections became curable, and average life expectancy rose sharply.

正解

第3段落 "Infections that had killed millions of people ... could suddenly be cured ... average life expectancy rose sharply in the decades that followed" より、影響 = 致命的感染症の治療 + 平均寿命の急上昇a course of treatment = 「一連の治療」、life expectancy = 「平均寿命」。

  • Penicillin became a usable medicine in 1928, years before mass production.

    = 1928年に即実用化 ━ 本文 "It took more than a decade" と矛盾。

  • Penicillin had almost no effect on infections that had once been deadly.

    = 感染症にほぼ無効だった ━ 本文 "its effect was enormous" と矛盾。

  • Average life expectancy fell in the years after penicillin appeared.

    = ペニシリン登場後に寿命が低下 ━ 本文 "rose sharply" と逆。

Collocation
パターン意味
turn A into BAをBに変えるturn Fleming's observation into a usable medicine
in large amounts大量にproduced in large amounts
a course of treatment一連の治療a short course of treatment
describe A as BAをBと評するdescribed it as a miracle
life expectancy平均寿命average life expectancy rose sharply
例文
  • It took a decade to make penicillin usable.

    実用化に10年を要した。

  • Deadly infections could suddenly be cured.

    致命的感染症が突然治療可能になった。

  • Life expectancy rose sharply afterwards.

    その後平均寿命は急上昇した。

💡Tip · 覚えるコツ

影響設問の鉄則 ―― "its effect was enormous" 以下 (cured / miracle / soldiers survived / life expectancy rose) を拾う。誤答は本文を逆転 (即実用化 / 無効 / 寿命低下) で誘導。「10年以上かかった」も頻出ひっかけ。

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