EigoPro 準1級 読解 — The Ethics of Animal Testing

Few questions in bioethics divide opinion as sharply as the use of animals in research. To its defenders, the practice is an unfortunate necessity: nearly every modern vaccine, surgical technique, and cancer therapy was first refined on creatures whose physiology resembles our own. To its critics, it is an indefensible cruelty—the deliberate infliction of suffering on beings that cannot consent, justified by an arithmetic that values human convenience above animal pain. Between these poles lies a debate that resists easy resolution, precisely because both camps invoke genuine moral intuitions. The strongest case for testing rests on consequences. A drug that has never been tried on a living system cannot be declared safe; computer models and cell cultures, however sophisticated, fail to reproduce the bewildering complexity of a whole organism. Yet this defence concedes more than it admits. If animal models were truly reliable predictors of human outcomes, the high rate at which promising compounds fail in human trials would be inexplicable. The discrepancy suggests that the scientific value of animal data is often overstated, even as its moral cost is quietly discounted. Critics, for their part, rarely demand that all testing cease overnight. The more sophisticated argument invokes the principle of the "Three Rs"—replacement, reduction, and refinement—which urges scientists to substitute non-animal methods wherever possible, to use fewer animals, and to minimise the distress of those still used. This framework has the virtue of acknowledging that progress is gradual. It does not pretend that a cure for a child's leukaemia and the discomfort of a laboratory mouse weigh the same; rather, it insists that the burden of justification falls on those who would cause harm, not on those who question it. The real measure of a society, this view implies, is not whether it uses animals at all, but how seriously it interrogates each decision to do so.

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この単元の問題を3問、解説つきで公開しています

準1級 · 読解 · 全5

1

What is the main idea of the passage?

  • Animal testing pits two genuine moral intuitions against each other, and a measured framework matters more than either extreme.
  • Computer models have already replaced the need for any experiments on living animals.
  • Animal testing should be banned immediately because it has never produced any medical benefit.
  • Scientists and animal-rights critics in fact share identical views about laboratory research.
Phrase

Between these poles lies a debate that resists easy resolution, precisely because both camps invoke genuine moral intuitions.

準1級読解生命倫理 (論説)主旨把握
ひとことで

本文は動物実験を巡る2つの正当な道徳的直観の対立と、極論より節度ある枠組みの重要性を論じる。

選択肢の解説Choice Analysis

Animal testing pits two genuine moral intuitions against each other, and a measured framework matters more than either extreme.

正解

第1段で擁護派 (必要悪) と批判派 (許されぬ残酷) の両極を提示し both camps invoke genuine moral intuitions と述べる。第2・3段で双方の論を検討し、最終的に Three Rs という段階的枠組みを支持して『社会の真の尺度は各判断をどれだけ真剣に吟味するかだ』と結ぶ。よって『2つの正当な道徳的直観の対立であり、いずれの極端よりも節度ある枠組みが重要』が主旨。

  • Animal testing ought to be banned immediately because it has never once produced any medical benefit at all.

    = 即時全面禁止すべき/医学的恩恵は皆無 ━ 本文はワクチン・手術・がん治療が動物実験で精製されたと明記し、批判派も即時中止を求めないと述べているので二重に誤り。

  • Computer models have by now already entirely replaced the need for any kind of experiment upon living animals.

    = 計算モデルが既に代替済み ━ 第2段は computer models ... fail to reproduce the bewildering complexity と明言しており正反対。

  • Scientists and animal-rights critics in fact share entirely identical views about all forms of laboratory research.

    = 両者の見解は同一 ━ 本文は両者を opinion as sharply ... divide と対立させており同一ではない。

Collocation
パターン意味
divide opinion意見を二分するFew questions divide opinion as sharply.
an unfortunate necessityやむを得ない必要悪a practice seen as an unfortunate necessity
resist easy resolution簡単には決着しないa debate that resists easy resolution
invoke a principle原則を持ち出すBoth camps invoke moral intuitions.
between these polesこの両極の間にBetween these poles lies a debate.
例文
  • Few issues divide opinion as sharply as this one.

    これほど意見を二分する問題は少ない。

  • The practice is defended as an unfortunate necessity.

    その慣行はやむを得ない必要悪として擁護される。

  • The debate resists easy resolution.

    その議論は簡単には決着しない。

💡Tip · 覚えるコツ

論説文の主旨は第1段の対立提示と最終段の結論文を結ぶ。極端な全否定・全肯定の選択肢は『節度ある』論説の主旨とほぼ合わない。

2

According to the passage, what undermines the claim that animal models reliably predict human outcomes?

  • Researchers are legally barred from testing new drugs on living systems.
  • Computer models have proven more accurate than whole organisms in every case.
  • Many promising compounds that succeed in animals later fail in human trials.
  • Laboratory animals refuse to cooperate with most experimental procedures.
Phrase

the high rate at which promising compounds fail in human trials would be inexplicable

準1級読解生命倫理 (論説)詳細把握
ひとことで

動物で有望な化合物が人間の治験で高率に失敗する事実が、動物モデルの信頼性主張を崩す。

選択肢の解説Choice Analysis

Many promising compounds that succeed in animals later fail in human trials.

正解

第2段で『動物モデルが本当に信頼できる予測因子なら、有望な化合物が人間の治験で高率に失敗するのは説明がつかない』(the high rate at which promising compounds fail in human trials would be inexplicable) と述べる。この食い違い (discrepancy) が信頼性主張を崩す根拠なので、『動物で成功した多くの有望な化合物が後に人間の治験で失敗する』が正解。

  • animals refuse to cooperate

    = 動物が協力を拒む ━ 本文にそのような記述はない。問題は予測精度であって動物の協力ではない。

  • Computer models have proven more accurate than whole organisms in every case.

    = 計算モデルが全例で正確 ━ 第2段は計算モデルが全組織の複雑さを再現『できない』と述べており正反対かつ言い過ぎ。

  • legally barred from testing

    = 法的に禁止されている ━ 法的禁止の記述はなく、信頼性の議論とは無関係。

Collocation
パターン意味
a reliable predictor of ~~の信頼できる予測因子a reliable predictor of human outcomes
fail in trials治験で失敗するcompounds fail in human trials
the discrepancy suggests ~その食い違いは~を示唆するThe discrepancy suggests overstatement.
be overstated誇張されているthe value is often overstated
be quietly discountedひそかに過小評価されるits moral cost is quietly discounted
例文
  • Many promising compounds fail in human trials.

    多くの有望な化合物が人間の治験で失敗する。

  • Animal data is not a reliable predictor of human outcomes.

    動物データは人間の結果の信頼できる予測因子ではない。

  • The discrepancy suggests the value is overstated.

    その食い違いは価値が誇張されていることを示唆する。

💡Tip · 覚えるコツ

detail 設問では仮定法 (would be inexplicable) が論拠の核になることが多い。『もし~なら説明がつかない』=実際は~でない、という反実仮想の読み取りが鍵。

3

What does the principle of the "Three Rs" urge scientists to do?

  • Treat a child's illness and a mouse's discomfort as exactly equal in weight.
  • Increase the number of animals used in order to gather more data.
  • Replace animals where possible, use fewer of them, and reduce the suffering of those still used.
  • Halt all animal research immediately and without exception.
Phrase

to substitute non-animal methods wherever possible, to use fewer animals, and to minimise the distress of those still used

準1級読解生命倫理 (論説)詳細把握
ひとことで

Three Rs = 代替 (replacement)・削減 (reduction)・改善 (refinement) の三原則。

選択肢の解説Choice Analysis

Replace animals where possible, use fewer of them, and reduce the suffering of those still used.

正解

第3段で Three Rs を replacement, reduction, and refinement と定義し、それぞれ『可能な限り非動物法に代替』『使用数を減らす』『使われる動物の苦痛を最小化』と説明する。これを言い換えた『可能なら動物を代替し、使用数を減らし、なお使う動物の苦痛を軽減する』が正解。

  • Halt every form of animal research immediately and entirely without any exception.

    = 即時全面停止 ━ 本文は批判派も rarely demand that all testing cease overnight と述べており正反対。

  • Increase the total number of animals used in order to gather a great deal more data.

    = 動物の数を増やす ━ reduction (削減) と正反対。

  • Treat a child's illness and a mouse's discomfort as being exactly equal in weight.

    = 子供の病と鼠の不快を完全同等に扱う ━ 本文は does not pretend that ... weigh the same と明確に否定している。

Collocation
パターン意味
substitute A for B / substitute non-animal methodsBの代わりにAを使うsubstitute non-animal methods
wherever possible可能な限りreplace wherever possible
minimise the distress苦痛を最小化するminimise the distress of the animals
the burden of justification falls on ~立証責任は~にあるThe burden falls on those who cause harm.
acknowledge that ~~を認めるacknowledging that progress is gradual
例文
  • Scientists should substitute non

    animal methods wherever possible. — 科学者は可能な限り非動物法に代替すべきだ。

  • The framework aims to minimise the distress of the animals.

    その枠組みは動物の苦痛を最小化することを目指す。

  • The burden of justification falls on those who cause harm.

    立証責任は害を与える側にある。

💡Tip · 覚えるコツ

列挙型 detail 設問は本文の3要素 (replacement/reduction/refinement) が選択肢に正確に対応するかを照合。1つでも欠落・反転していれば誤答。

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